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Complex Systems Grantee Publishes Research in the Proceedings of the National Academy of Sciences


Philip LeDuc
Complex Systems Grantee Philip LeDuc published an article "Defining the role of syndecan-4 in mechanotrandsuction using surface-modification approaches" in the December 29, 2009 issue of the Proceedings of the National Academy of Sciences (PNAS). 

In cancer and wound healing, one of the critical factors between more treatable primary cancer and secondary cancer which has spread throughout the body is the ability for cells to leave the primary tumor and crawl to other places in the body through the bloodstream.  The process of cell crawling is heavily influenced by MechanoBiology and this protein, syndecan, is part of that.  If the link between MechanoBiology and syndecan-4 can be better understood, new directions for cancer and wound healing treatments could be made.

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